内镜下局部化疗联合内支架置入治疗食管癌性狭窄30例疗效观察

Observation of therapeutic effects of endoscopic local chemotherapy combined with stent implantation in the treatment of 30 patients with esophageal cancerous stricture

目的评价内镜下局部注射化疗药物并置入支架治疗食管癌性狭窄的疗效。方法 30例患者经内镜及病理确诊为晚期食管癌,均局部注射化疗药物后置入支架治疗,在癌体基底周边及中央注射药物5-FU及顺铂,再置内支架。结果吞咽困难缓解率为100%,癌体缩小有效率60%。结论内镜下局部注射化疗药物并置入内支架治疗食管癌性狭窄是一种较为理想和有效的方法,其操作简单,易于掌握。

Objective To value the therapeutic effects of endoscopic local injection of chemotherapentic drugs combined with stent implantation in the treatment of esophageal cancerous stricture. Methods Thirty patients with endoscopically and pathologically proved esophageal cancerous stricture received endoscopic local injection of 5- FU and cisplatin around cancer body and in the centre and the basement of cancer body, and then received stent im- plantation. Results The reminssion rate of dysphagia was 100% ; the effective reduction rate of cancer body was 60%. Conclusion Endoscopic local injection of chemotherapentic drugs combined with stent implantation in the treatment of esophageal cancerous stricture is a comparative effective method. It is simple and easy to master.