急性心肌梗死PCI术前应用盐酸替罗非班对患者心肌坏死标记物的影响

目的探讨急性心肌梗死PCI术前应用盐酸替罗非班对患者心肌坏死标记物的影响。方法 92例急性心肌梗死行急诊PCI术的病人中48例入院确诊为急性心肌梗死后立即给予盐酸替罗非班后行急诊PCI设为治疗组;44例术前不给盐酸替罗非班仅行急诊PCI术作为对照组。两组术前均嚼服阿司匹林片300mg,硫酸氢氯吡格雷片600mg,两组患者术前、术后24h分别检测磷酸肌酸激酶同工酶(CK-MB)、肌钙蛋白T(cTnT)。结果术后24h两组心肌梗死标记物与术前相比明显升高(P<0.05);术后24h对照组与治疗组相比心肌梗死标记物有明显差异(P<0.05)。结论早期应用盐酸替罗非班可减轻心肌的坏死。

Objective PCI of acute myocardial infarction preoperative application hydrochloride Tirofiban in patients with myocardial necrosis spot on the impact of markers.Methods 92 cases of hospital patients with acute myocardial infarction patients with emergency PCI patients,of which 48 cases admitted to hospital diagnosed as acute myocardial infarction immediately Tirof iban Hydrochloride spot later emergency PCI as the treatment group;44 cases of preoperative do not give hydrochloride for Luo Non-spot only emergent PCI operation as the control group.Preoperatively chewing aspirin tablets 300mg;clopidogrel bisulfate tablets 600mg;two groups of patients with preoperative and postoperative 24h phosphoric acid were used to detect creatine kinase isoenzyme （CK-MB）,troponin T （cTnT）.Results Group 24hPCI after myocardial infarction markers compared with the preoperative significantly higher （P0.05）;after 24h control group and treatment group compared with preoperative myocardial infarction marker Ariake difference （P0.05）.Conclusion Early application hydrochloride Tirofiban spot reduce myocardial necrosis.