脾动脉栓塞治疗慢性特发性血小板减少性紫癜51例疗效观察

Effect of partial splenic artery embolism in treatment of chronic idiopathic thrombocytopenic purpura

目的回顾性分析脾动脉栓塞治疗特发性血小板减少性紫癜的临床疗效。方法选择5l例药物治疗无效的特发性血小板减少性紫癜,采用seldinger技术对脾动脉进行部分栓塞,栓塞面积约80%左右,并于术后定时复查血常规,观察其疗效。结果手术的即时性疗效为50例(98.0%),近期疗效为41例(80.4%),远期疗效为66.7%。结论对内科治疗无效的特发性血小板减少性紫癜部分脾动脉栓塞术是一种较理想的治疗方法。

Objective To retrospectively analyze clinical effect of partial splenic embolization in treatment of idiopathic thrombocytopenic purpura.Methods 51 cases of idiopathic thrombocytopenic purpura failed by medicine were treated with embolization of partly splenic artery using Seldinger technique.The embolization area of splenic artery was about 80%.The blood routine examination was performed regularly and the effect for treatment was evaluated.Results There were 50 cases（98.0%） with instant effect and the curative effect for the 41 cases（80.4%）.0.5a and above long term effect was 66.7%.Conclusion Partial splenic embolization is an ideal treatment for refractory to medical therapy of chronic idiopathic thrombocytopenic purpura.