来曲唑与克罗氯米芬应用于多囊卵巢综合征患者促排卵效果的比较研究

Comparative research on the effect of ovulation induction of letrozole and clomiphene crowe application in patients with polycystic ovary syndrome

目的:比较来曲唑与克罗氯米芬应用于多囊卵巢综合征患者的促排卵效果。方法:将该院2008年2月～2009年1月收治的76例多囊卵巢综合征患者随机分为两组,对照组38例采用克罗氯米芬治疗,观察组38例采用来曲唑治疗,比较分析两组的促排卵效果。结果:观察组的治愈率为18.4%,明显高于对照组的2.6%,两组间差异有统计学意义(P<0.05);观察组HCG注射日子宫内膜厚度为(9.14±1.35)mm,对照组为(5.39±0.62)mm,两组间差异有统计学意义(P<0.05)。结论:来曲唑应用于多囊卵巢综合征患者,疗效肯定,有利于子宫内膜的发育情况,值得在临床推广应用。

Objective：To compare the effect of ovulation induction of letrozole and clomiphene crowe application in patients with polycystic ovary syndrome （PCOS）.Methods：76 patients with PCOS in the hospital from February 2008 to January 2009 were divided into two groups randomly：38 cases in control group were treated with clomiphene crowe,38 cases in observation group were treated with letrozole;the effect of ovulation induction of the two groups were compared and analyzed.Results：The cure rate in observation group was 18.4%,which was significantly higher than that in control group （2.6%）,there was significant difference （P 0.05） ;the endometrial thicknesses on the day of HCG injection were （9.14 ± 1.35） mm in observation group and （5.39 ± 0.62） mm in control group,there was significant difference （P 0.05）.Conclusion：Letrozole used in patients with PCOS is effective and conducive to the development of endometrium,which is worth popularizing.