雌激素在药物流产中的应用

Application of estrogen in medical abortion

目的:探讨补佳乐在药物流产后缩短出血时间、促进内膜修复和月经恢复的作用。方法:将早孕行药物流产者60例随机分为试验组和对照组,试验组在孕囊排出后第2天开始口服补佳乐1mg,2次/d,共21天。观察两组阴道出血时间、清宫率及月经恢复时间。结果:试验组和对照组在阴道出血时间、清宫率及月经恢复时间方面差异均有统计学意义。结论:药物流产后加用补佳乐可以通过促进子宫内膜增生、修复的作用,从而缩短出血时间、促进月经周期恢复、减少清宫率,进一步提高药物流产的成功率及满意度,减少并发症。

Objective：To observe the effect of estrogen on vaginal bleeding duration, endometrium repair and menstruation restoration in medical abortion.Methods：60 women with medical abortion were randomly divided into observation （Progynova orally, twice a day for 21 days） and control groups. Vaginal bleeding duration, endometrium repair and menstruation restoration were analysed.Results：Vaginal bleeding duration, curettage use and menstruation restoration had significant differences between two groups.Conclusion：Estrogen can promote menstruation restoration, shorten bleeding duration and decrease curettage rate.