化妆品安全性风险评估的方法

The Method of Cosmetic Risk Assessment

化妆品安全性风险评估是化妆品安全体系的核心与基础，可分为危害识别、危害特征描述、暴露评估以及风险特征描述四个步骤。化妆品安全性风险评估主要依赖于毒理学手段，同时还需要利用化学、物理学、计算和统计科学等多学科交叉的方法才可实现。随着动物保护意识的增强，毒理学替代法的应用研究已成为重要的发展方向之一。

Cosmetic risk assessment is the basic and core of the cosmetic safety system. It contains four parts, including hazard identification, dose-response assessment, exposure assessment and risk characterization. Most methods of the cosmetic risk assessment are come from toxicology. However, cosmetic risk assessment still requires a multi-disciplinary approach covering detailed knowledge of chemistry, physics and statistics, etc. As awareness of animal protection enhances, toxicology substitution methods are one of the important of development.