黄体中期血清孕酮测定和子宫内膜活检在不孕症诊断中的意义

The significance of progesterone profile and endometrial biopsy during luteal median phase in diagnosis of infertile women

目的对原因不明不孕症患者的黄体中期行血清孕酮测定和子宫内膜活检,寻找不孕的原因及其在诊断中的意义。方法对58例不孕症患者黄体中期(排卵后第7天)检测血清孕酮水平,同时取子宫内膜病理检查。结果 58例不孕症患者中黄体中期分泌延迟46例,分泌正常12例(P(0.01)。血清孕酮水平(47.7nmol/L30例,≥47.7nmol/L28例(P(0.05)。在分泌延迟的46例不孕症患者中,60.87%黄体中期血清孕酮水平(47.7nmol/L,39.13%≥47.7nmol/L(P(0.01)。结论黄体中期行血清孕酮测定和子宫内膜活检更易发现患者不孕的原因。对于不孕症的诊断和指导治疗具有重要的意义。

Objective To investigate the significance of progesterone profile and endometrial biopsy during luteal median phase in diagnosis of infertile women.Methods The progesterone profiles during median luteal phase and endometrial histology during median luteal phase in 58 infertile women were studied.The biopsy of endometrium was carried out as well.Results Retarded endometrial development occurred in the median luteal phase in 46 of the 58 cases（P﹤0.01）.The progesterone profile of these patients was markedly lower compared with the control group（P﹤0.05）.Conclusion The progesterone profile during median luteal phase and endometrial biopsy during median luteal phase can judge infertile reasons,and has an important significance for diagnosis and treatment.