妊娠期肝内胆汁淤积症病人围生期的监测及护理

Perinatal monitoring and nursing care of pregnant women with intrahepatic cholestasis

[目的]探讨妊娠期肝内胆汁淤积症(ICP)围生期的监测及护理。[方法]对131例ICP病例资料进行回顾性分析。[结果]共发现羊水胎粪污染49例,其中羊膜腔穿刺发现6例,人工破膜发现34例,剖宫产手术中发现4例,自然破膜发现5例。羊水污染率37.4%,早产率26.0%,剖宫产率62.6%,均高于同期分娩的非ICP病人(P<0.05),无围生儿死亡。[结论]对妊娠期肝内胆汁淤积症及早发现、正确处理及护理,避免胎儿宫内缺氧及胎儿死亡等不良后果发生。

Objective：To probe into the perinatal monitoring and nursing care of pregnant women with intrahepatic cholestasis （ICP）.Methods：Clinical data of 131 pregnant women with intrahepatic cholestasis were analyzed retrospectively.Results：Among all 131 cases,49 cases were with meconium staining of amniotic fluid.Among them,6 cases were detected by amniocentesis,34 cases by induced rupture of membrane,4 cases by cesarean section and 5 cases by spontaneous rupture of membrane.The rate of amniotic fluid meconium staining was 37.4%.The rate of premature delivery was 26.0%.And the rate of cesarean section was 62.6%.All of which were significantly higher in ICP patients than that in normal pregnant population of the same gestational age（P〈0.05）.There was no perinatal death.Conclusion：Early detection of intrahepatic cholestasis of pregnant women,and to handle and to provide nursing correctly may avoid badness consequence of fetal intrauterine hypoxia or fetal death.