口腔扁平苔藓与免疫球蛋白关系的初步研究

Preliminary study of immuno blobulion and oral lichenplanus

目的探讨口腔扁平苔藓（ＯＬＰ）患者的免疫球蛋白与ＯＬＰ发病过程的关系。方法分别测定５３名ＯＬＰ患者和３０名健康对照组的血清免疫球蛋白ＩｇＡ、ＩｇＧ、ＩｇＭ及唾液免疫球蛋白ＳＩｇＡ、ＩｇＧ。结果ＯＬＰ组血清ＩｇＧ增高，唾液ＳＩｇＡ降低，与对照组比较有显著性差异。结论提示机体免疫机能平衡失调，可导致该疾病的发生，局部免疫力降低，随时引起ＯＬＰ的继发性感染。

Objectives To evaluate the relationshin between the immune blobulion and the develonment of oral lichen planus.Methods Writers measured blood-immunoglobulion;IgA,IgG,IgM and salivary-immunoglobulion:SIgA,IgG in 53 cases with oral lichen planus and 30 countrols.Results The results showed that the level of blood IgG was significantly higher in the patients than the countrols,and the level of salivary SIgA was significantly lower in the natients than the controls.Conclusion It indicates that the imbalance of the bodily immune functione leads to OLP and that the decrease of local immunity can cause secondlary infection of OLP