摘要
以邻苯二酚、二氯甲烷为起始原料,于碱性130℃条件下环化得到胡椒环,然后与乙酰氯于冰浴条件下经Friedel-Crafts酰基化得到3,4-亚甲二样基苯乙酮,最后经过Bayer-Villiger氧化、水解酸化得到目标产物芝麻酚,总产率达36.6%。对各个步骤中催化剂的种类对产率的影响进行了对比,并得出优化条件;对各步骤的主产物进行了提纯及结构的分析鉴定。
Using catechol and methylene chloride as strating material by cyclizing process, 1,3-benzodioxols was obtained,then reacted with acetyl chloride though the Friedel-Crafts acylation under the ice-bath condition, obtained 3,4- methylenedioxyacetophenone, got the final production of sesamol reacted in Bayer-Villiger oxidation, hydrolysis and acidification processes the whole yield of sesamol was 36.6%.The type of catalyst on yield was compared with each other in various steps and the optimum conditions obtained.The main products of steps was purified and structure was identified.
出处
《食品工业科技》
CAS
CSCD
北大核心
2010年第10期328-331,共4页
Science and Technology of Food Industry
基金
广东高校科技成果转化项目(cgzhzd0805)