冠醚取代的氨基酸Schiff碱及其金属配合物的合成、表征和抑菌活性研究

Synthesis, characterization and antibacterial activities of Schiff base metal Complexes derived from crown-ether substituted n-salicylidenealanine acid

合成了与单氮杂15-冠-5键连的水杨醛缩丙胺酸(H_2L^1)和水杨醛缩组氨酸(H_2L^2)Schiff碱和它们的Cu(Ⅱ)和Zn(Ⅱ)配合物.其结构由IR,~1H NMR,热重分析,摩尔电导和元原素分析表征.初步抑菌实验表明,配体和配合物都具有一定的抑菌活性.

Two Schiff base ligands prepared via the condensation of N-（3-formyl-4- hydroxybenzyl） aza15-crown-5 with L-Ana（H2L1）and L-His（H2L2）, and their Cu（ Ⅱ） and Zn（ Ⅱ）complexes were charae-terized by IR, 1HNMR, thermoanalysis, molar conductance and elemental analysis. In primary test of their antibacterial activities, both the ligands and their complexes showed antimierobial activities againstbacterial.