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比索洛尔、氯沙坦联合用药对高血压病患者左室重构和左心室舒张功能的影响 被引量:1

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摘要 目的:观察比索洛尔、氯沙坦治疗高血压病12个月前后患者左室重构和左室舒张功能的疗效。方法:46例轻中度高血压病患者使用比索洛尔5mg和氯沙坦50mg,连服12个月,治疗前后用超声测定左心室结构和舒张功能改变。结果:治疗12个月后左心室重量指数降低(P<0.05),舒张期末室间隔厚度和左心室后壁厚度变薄(P<0.05),左心室舒张末内径缩小(P<0.05),E/A增加(P<0.05)而射血分数变化不大。结论:比索洛尔、氯沙坦联合用药治疗高血压的同时,能逆转左室重构,明显改善左室舒张功能。
出处 《中国社区医师(医学专业)》 2010年第29期16-17,共2页
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