期刊文献+

缬沙坦治疗老年心力衰竭疗效观察

下载PDF
导出
摘要 目的:观察缬沙坦治疗老年慢性心力衰竭(CHF)患者的疗效。方法:将59例老年慢性心力衰竭患者随机分为两组,缬沙坦组除常规抗心衰治疗外加用缬沙坦。结果:治疗3个月时,左室收缩末内径、左室舒张末内径两组之间差异无统计学意义,但左室射血分数、舒张早期和舒张晚期血流峰速度比值(Ep/Ap)、左室后壁厚度、室间隔厚度缬沙坦组显著低于对照组(P<0.05)。结论:缬沙坦治疗老年慢性心力衰竭疗效肯定。
作者 韩自华 沙金
出处 《中国社区医师(医学专业)》 2010年第28期35-35,共1页
  • 相关文献

参考文献2

二级参考文献14

  • 1MITROV1C V, WILLENBROCK R, MIRIC M, et al. Acute and 3-month treatment effects of candesartan cilexetil on hemodynamics, neurohormones, and clinical symptoms in patients with congestive heart failure[J]. Am Heart J, 2003, 145(3): E14.
  • 2SAKATA Y, YAMAMOTO K, MASUYAMA T, et al. Ventricular production of natriuretic peptides and ventricular structural remodeling in hypertensive heart-failure[J]. J Hypertens, 2001,19(10): 1905-1912.
  • 3FENTON C, SCOTT LJ. Candesartan cilexetil: a review of its use in the management of chronic heart failure[J]. Drugs, 2005,65(4): 537-558.
  • 4MATSUMORI A. Efficacy and safety of oral candesartan cilexetil in patients with congestive heart failure[J]. Eur J Heart Fail, 2003,5(5) : 669-677.
  • 5GLEITER CH, MORIKE KE. Clinical pharmacokinetics of candesartan[J]. Clin Pharmacokinet, 2002, 41 ( 1 ) : 7-17.
  • 6MELIAN EB, JARVIS B. Candesartan cilexetil plus hydrochlorothiazide combination:a review of its use in hypertension[J]. Drugs, 2002, 62(5): 787-816.
  • 7PFEFFER MA, SWEDBERG K, GRANGER CB, et of. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme[J]. Lancet,2003, 362(9386): 759-766.
  • 8McMURRAY JJ, OSTERGREN J, SWEDBERG K, et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial[J]. Lancet,2003, 362(9386): 767-771.
  • 9GRANGER CB, McMURRAY JJ, YUSUF S, et ol. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial[J]. Lancet, 2003, 362(9386): 772-776.
  • 10YUSUF S, PFEFFER MA, SWEDBERG K, et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved trial[J].Lancet, 2003, 362(9386): 777-781.

共引文献2416

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部