摘要
目的探讨参麦注射液不良反应的规律及特点,为临床合理用药提供参考。方法收集中山市人民医院2008~2009年上报广东省药品不良反应(ADR)监测中心的参麦注射液不良反应的病例,检索1994~2009年国内公开发行的医学期刊报道的应用参麦注射液后发生不良反应的病例,进行统计分析。结果参麦注射液不良反应多发生于40岁以上年龄组,女性多于男性,其ADR出现时间多在用药过程中30min内发生。不良反应临床表现复杂多样,以过敏反应居多。结论临床医师、药师应重视参麦注射液的不良反应,加强其应用过程中的监测,谨慎用药。
Objective To explore the general rule and the characteristics of adverse drug reaction(ADR) induced by Shenmai injection and to provide some references for clinical medicine and rational use of drug. Methods One part of the ADR reports were collected by Zhongshan People's Hospital of 2008 to 2009, another part of the reports were collected by national journals of 1994 to 2009. 170 ADR reports were analyzed using retrospective study method. Results ADR appeared mostly in the 40 age group, and more in female. The onset of ADR was usually within the first 30 min during the infusion. and the clinical manifestations of ADR were various, of which the allergic reaction was the most common. Conclusion Doctors and pharmacists should pay more attention to the ADR of Shenmai injection for the Immediate allergic reaction.
出处
《中国药物警戒》
2010年第10期623-625,共3页
Chinese Journal of Pharmacovigilance