慢性阻塞性肺疾病急性加重期患者静脉血栓栓塞的发生率及预防

Prevalence and prevention of venous thromboembolism in patients with acute exacerbations of chronic obstructive pulmonary disease

静脉血栓栓塞（venous thromboembolism，VTE）是一种常见疾病，慢性阻塞性肺疾病（chronic obstructive pulmonary disease，COPD）急性加重期的患者是发生VTE的危险因素。VTE是COPD急性加重期患者常见的潜在致命的并发症，肺栓塞亦是COPD患者死亡相对常见的原因。然而关于COPD急性加重期的VTE发生率及预防的报道很少。通过检索与此相关的文献，大部分临床资料显示肝素可以显著降低VTE的发生率，为评估COPD急性加重期患者所有有关VTE的发生率和预防的有效信息，为临床工作提供依据，本文将对此进行综述。

Venous thromboembolism（VTE） is a common disord. Patients with acute exacerbations of chronic obstructive pulmonary disease （COPD） are considered to be at moderate risk for the development of VTE. VTE is a common and potentially fatal complication in patients with acute exacerbations of COPD. Pulmonary embolism is a relatively frequent cause of death in patients with COPD. Little information exists on the prevalence and prevention of VTE in patients admitted for acute exacerbations of COPD. The most results of clinical trials indicate that heparin significantly reduce VTE rates. To evaluate the information on the prevalence and prevention of VTE in patients with acute exacerbations of COPD,a systematic review of the literature was carried out.