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循环肿瘤细胞检测及其临床应用 被引量：1

Detection and clinic implication of circulating tumor cells in peripheral blood
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摘要 循环肿瘤细胞（CTC）与恶性肿瘤的发生发展密切相关。目前检测CTC的方法有逆转录聚合酶链反应、免疫磁珠富集检测法等。检测CTC有助于发现早期肿瘤患者的微转移、重新确定临床分期，监测术后或者放化疗后患者肿瘤复发与转移，评估预后，选择个体化的治疗策略。 Circulating tumor cells are closely related to the development and progression of malignant tumors. Current methods of detecting circulating tumor cells include reverse transcription polymerase chain reaction method and immunomagnetic enrichment assay. Detection of circulating tumor cells can contribute to early detection of cancer micrometastases, re-classification of clinical stage, monitoring recurrence and metastasis after surgery or radiotherapy and chemotherapy, predicting prognosis, and selecting personalized therapeutic strategy.
作者 徐刚(综述) 于雁(审校)
机构地区 哈尔滨医科大学附属肿瘤医院内六科
出处 《国际肿瘤学杂志》 CAS 2010年第9期668-671,共4页 Journal of International Oncology
关键词 循环肿瘤细胞 肿瘤转移 免疫磁珠 逆转录聚合酶链反应 Circulating tumor cells Neoplasm metastasis Immunomagneticbeads Reverse transcriptase polymerase chain reaction
分类号 R739.91 [医药卫生—肿瘤]
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参考文献20

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共引文献47

同被引文献26

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国际肿瘤学杂志
2010年 第9期

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