摘要
目的:观察加味小陷胸汤干预湿热困脾型糖耐量受损,评价其疗效。方法:70例湿热困脾型糖耐量受损患者随机分为治疗组(n=33例)和对照组(n=37例),在生活方式干预的基础上,治疗组服加味小陷胸汤,对照组服二甲双胍片,观察治疗前后2组患者证候、血糖、胰岛素释放及其敏感性、胰岛素抵抗指数等改善情况。结果:治疗组患者在证候积分、血糖积分、胰岛素敏感性、体重指数、腰围、臀围与对照组比较有统计学意义。结论:加味小陷胸汤能显著改善患者中医临床症状,降低患者血糖积分,提高胰岛素敏感性,减轻体重,减小腰围,且无不良反应。
Objective:To observe and evaluate the therapeutic effects of modified Minor Chest Bind Decoction on impaired glucose tolerance(IGT) in the pattern of dampness-heat accumulating spleen.Methods:60patients of the abovementioned syndrome were randomized to treatment group (n=30) and control group (n=30),respectively treated with the decoction and metformin,besides life style intervention. Changes in syndromes,glucose,insulin releasing,insulin sensitivity,insulin resistance exponent were observed.Results:Treatment group was significantly different from control group in syndrome score,glucose score,insulin sensitivity,BMI,waist line,hip line.Conclusion:The decoction can significantly relieve the dampness-heat syndrome,lower glucose,enhance insulin sensitivity,reduce weight and waist line,while having little adverse reactions.
出处
《世界中医药》
CAS
2010年第5期317-319,共3页
World Chinese Medicine
基金
上海市虹口区医学科研重大课题(0801 -01)
关键词
糖耐量受损/中医药疗法
加味小陷胸汤
湿热困脾
Impaired glucose tolerance/ Chinese medical therapy
Modified Minor Chest Bind Decoction
dampness-heat accumulating spleen