静滴川芎嗪并雾化吸入低分子肝素钙治疗慢性肺心病疗效观察

Intravenous infusion of TMP,and inhalation of low molecular weight heparin efficacy of the treatment of chronic pulmonary heart disease

目的探讨静滴川芎嗪并雾化吸入低分子肝素钙治疗慢性肺源性心脏病(简称肺心病)的价值。方法 60例肺心病急性加重期住院患者,随机分为治疗组与对照组,对照组给予常规治疗,治疗组在常规治疗的基础上,加用川芎嗪静滴并低分子肝素钙雾化吸入。结果治疗10天后,治疗组较对照组血液流变学指标明显改善,PaO2明显上升,PaCO2明显下降。治疗组临床总有效率93.3%,明显高于对照组76.7%(P<0.05)。结论静滴川芎嗪并雾化吸入低分子肝素钙可明显改善肺心病患者的血液粘稠度和肺通气功能,提高临床总有效率,给药方便、安全有效。

Objective To investigate the intravenous infusion of TMP,and inhalation of low molecular weight heparin treatment of chronic pulmonary heart disease （cor pulmonale） value.Methods 60 patients with pulmonary heart disease inpatients with acute exacerbation were randomly divided into treatment group and control group and control group was given conventional therapy,the treatment group in the conventional treatment,based on TMP infusion was added,and low molecular weight heparin calcium aerosol inhalation.Results after 10 days,the treatment group than in the control group significantly improved hemorheology,PaO2 significantly increased,PaCO2 decreased significantly.Treatment group the total effective rate was 93.3%,significantly higher than 76.7% （P0.05）.Conclusion Intravenous TMP and inhalation of low molecular weight heparin in patients with pulmonary heart disease can be significantly improved blood viscosity and pulmonary function,improve the clinical total effective dose convenient,safe and effective.