影响慢性重型乙型肝炎患者预后的因素

Factors affecting the prognosis of chronic severe hepatitis B

目的:分析影响慢性重型乙型肝炎患者预后的各种因素,进一步指导临床诊治。方法:总结96例慢性重型乙型肝炎患者的病例资料,将患者分为病死组及好转组,分析两组患者年龄、血清中HBV-DNA载量、PTA、AFP、CHOL、CHE。结果:患者年龄越大、HBV-DNA载量越高,其病情进展越快,预后越差;PTA、AFP、CHOL、CHE越低预后越差,死亡率越高。结论:年龄、HBV-DNA载量、PTA、AFP、CHOL、CHE均是影响慢性重型乙型肝炎预后的重要因素。

Objective：To analyze the factors affecting the prognosis of chronic severe hepatitis B,than direct the treatment.Methods：There 96 patients with severe hepatitis B were selected and divided into improved group and death group.Analyzed the patients＇ age,levels of serum HBV-DNA,prothrombin activity（PTA）,alpha fetoprotein（AFP）,cholesterol（CHOL）,cholinesterase（CHE）.Results： The patients who were older and has a higher level of serum HBV-DNA had a worse prognosis.And the lower of PTA,AFP,CHOL and CHE had a higher mortality.Conclusions： The age,level of serum HBV-DNA,PTA,AFP CHOL and CHE are important factors affecting prognosis of hepatitis B.