天眩清联合高压氧治疗急性高原脑水肿16例

Efficacy Observation of Gastrodin Injection with Hyperbaric Oxygen in the Treatment of Acute High Altitude Cerebral Edema

目的探讨天眩清注射液在高原脑水肿治疗中的应用价值。方法对我院20032008年收住高原脑水肿病例36例分为对照组（高压氧治疗）与治疗组（天眩清联合高压氧治疗）,其中对照组20例,治疗组16人,两组患者在病情严重程度、年龄、性别等方面无统计学差异,观察两组患者临床症状缓解情况。结果天眩清联合高压氧治疗组在头痛、头晕、认知功能障碍等症状改善程度方面明显高于对照组,无不良反应。结论天眩清联合高压氧治疗对改善高原脑水肿患者多数临床症状具有较好的效果,其作用机制值得临床与实验室进一步探讨。

Objective To investigate the application value of Gastrodin Injection in the treatment of acute altitude cerebral edema. Methods 36 cases of high altitude cerebral edema hospitalized in our hospital during 2003 - 2008 were divided into the control group （treated with hyperbaric oxygen） and the therapeutic group （treated with gastrodin injection and hyperbaric oxygen）. There were 20 cases in the control group and 16 cases in the therapeutic group. There was no statistical difference in severity of the condition, age, sex, etc. The release of the clinical symptoms of the patients was observed. Results Gastrodin injection with hyperbaric oxygen group was obviously better than the control group on the improvement of symptoms like headache, dizziness and cognitive disorders. No adverse reaction was observed. Condusion Gastrodin injection with hyperbaric oxygen has a favorable result on improving most clinical symptoms of high altitude cerebral edema. Its mechanism needs further clinical and experimental investigation.