摘要
目的探讨血浆B型尿钠肽（BNP）与心功能不全的关系。方法根Framingham诊断标准纳入的58例心功能不全患者，按NYHA分级。采用Triage快速定量测定仪检测BNP。结果从Ⅰ级～Ⅳ级各组患者，BNP水平逐渐升高；心功能Ⅳ级BNP水平高于心功能Ⅱ级组和Ⅲ级组（P均小于0．05）；而心功能Ⅱ级、Ⅲ级和Ⅳ级组均高于心功能Ⅰ级组（P均小于0．05）。结论BNP将成为评价心脏功能状态的一个常规检查，成为心功能不全的危险分层的指标。
Objective To study the relation between plasmaBNP level change and degree of chronic heart dysfunction. Methods 58 patients was diagnosed to chronic heart dysfunction by Framingham criteria, and were grouped into 4 groups according to NYHA class Ⅰ , Ⅱ, Ⅲ and class IV. Plasma BNP levelwere detected by Triage rapid measuremachine. Results BNP levelwas gradually increasing from class Ⅰ group to class Ⅳ group. BNP level in class Ⅳ group was significantly higher than in class Ⅱ,Ⅲ group （ P 〈 0.05）. BNP level in class Ⅱ, Ⅲ and class Ⅳ group was higher than in class I group （ P 〈 0.05）. Conclusion BNP may be a routine method to evaluate heart function and can evaluate prognosis in heart dysfunction.
关键词
血浆
BNP
心功能不全
Blood plasma
BNP
Heart incomplete function
