脑脉泰治疗脑血栓形成的临床观察

Clinical observation on cerebral thrombosis with naomaitai capsule

目的观察脑脉泰治疗脑血栓形成的临床疗效。方法采用随机分组将335例脑血栓形成患者分为治疗组和对照组A、对照组B、对照组C。治疗组88例用脑脉泰胶囊，对照组A83例用溶栓胶囊，对照组B79例用络欣通胶囊，对照组C85例用偏瘫复原丸，连续治疗3个月观察疗效。结果治疗组愈显率为82．96％（73／88），有效率为96．59％（85／88），与对照组A、对照组B、对照组比较差异有显著性（P〈0．01）；血液流变学及头部CT改变也有显著差异（P〈0．01）。安全性检测表明脑脉泰胶囊对心、肝、肾及周围血象无毒副作用。结论脑脉泰胶囊具有扩张血管，增加脑缺血动脉分布区血流量、溶栓抗凝、减少脑梗死面积、促进脑侧支循环建立、促进脑细胞和脑神经功能恢复等多方面的作用，是治疗脑血栓形成安全有效的药物。

Objective ： To observe the Clinical observation on cerebral thrombosis with naomaitai capsule. Methods ： 335 cases of cerebral thrombosis were randomly divided into four groups ; the treated group and the controlled group A, the controlled group B, the controlled group C. The treated group （88cases） treated by NaoMaitong capsule, The controlled group A （83cases） treated by Rongshuan capsule, The controlled group B （79cases） treated by Luoxintong capsule and the controlled group C （85cases） treated by Piantanfuyuanwan, and their therapeutic effectiveness were observed after 3 months constant treatment. Results ： The treated group had an effectual rate of 82. 65 % and effective rate of 96. 93 % , compared with the controlled group , the difference had significance （ P 〈 0. 01 ） . There was also great difference （ P 〈 0. 01 ） between two groups as to blood theology and change of head CT. Safety test indicates that there is nonpoisonous side-effect in heart , liver , kidney and surrounding blood with naomaitai capsule. Conclusion ; Naomaitai Capsule has the function of expanding blood vessel , increasing the blood flow of cerebral ischemia arterial area , dissolving thrombus and preventing blood coagulation , reducing the cerebral infarction area and promoting the establishment of cerebral side branch circulation and the recovery of cerebral cells and cerebral neural function. It has a better therapeutic effectiveness for apoplexy sequela.