小儿手足口病621例及并发症分析

Presentation and complication of hand,foot,and mouth disease: analysis of 621 cases.

目的总结小儿手足口病发病的临床特点和治疗经验。方法对2008年5月至2008年9月我院感染科621例手足口病住院患儿作回顾性分析,对其临床特征、并发症和治疗转归加以总结。结果本病好发于5岁以下儿童(94.69%),皮疹发生率为10O%,发热82.61%,经治病例中238例(38.32%)有并发症,脑炎155例(24.96%),神经源性肺水肿、肺出血1例(0.16%),无死亡病例。结论儿童手足口病应早期诊断治疗,注意筛查危重症病人,及时采取对策,预后大多良好。

Objective To summarize the clinical features and treatment experience of hand,foot,and mouth disease in children.Methods The clinical features and prognosis of 621 cases of children hand,foot,and mouth disease hospitalized in our hospital from May 2008 to September 2008 were retrospectively analyzed.Results Of the 621 cases,94.69% were children under 5 years of age.The incidences of rash and fever were 100% and 82.61% respectively.Complications were found in 238 cases（38.32%） including encephalitis in 155 cases（24.96%）,and neurogenic pulmonary edema and pulmonary hemorrhage in one case（0.16%）.No death occurred.Conclusion Early diagnosis and treatment,and screening and timely treatment of critically ill patients will improve the prognosis of hand,foot,and mouth disease in children.