2Andre T,Bensmaine M, Louvet C, et al. Multicenter phase Ⅱstudy of bimonthly high-dose leucovorin, fluorouracil infusion, and oxaliplatin for metastatic colorectal cancer resistant to the same leucovorin and fluorouracil regimen[J].J Clin Oncol, 1999,17:3560-3568.
3Wilson RH, Lehky T, Thomas RR, et al.Acute oxaliplatin-induced peripheral nerve hyperexcitability[J].J Clin Oncol, 2002,20:1767-1774.
4Lehky TJ, Leonard GD, Wilson RH, et al. Oxaliplatin-induced neurotoxicity: acute hyperexcitability and chronic neuropathy[J]. Muscle Nerve, 2004,29(3):387-392.
5Grolleau F,Gamelin L, Boisdron-Celle M, et al.A possible explanation for a neurotoxic effect of the anticancer agent oxaliplatin on neuronal voltage-gated sodium channels[J]. J Neurophysiol, 2001,85:2293-2297.
6Lersch C, Schmelz R, Eckel F, et al. Prevention of oxaliplatin-induced peripheral sensory neuropathy by carbamazepine in patients with advanced colorectal cancer[J]. Clin Colorectal Cancer, 2002,2:54-58.
7Gamelin L,Boisdron-Celle M, Delva R, et al. Prevention of oxaliplatin-related neurotoxicity by calcium and magnesium infusions: a retrospective study of 161 patients receiving oxaliplatin combined with 5-Fluorouracil and leucovorin for advanced colorectal cancer[J].Clin Cancer Res, 2004,10(12 Pt 1):4055-4061.
8Cascinu S,Catalano V,Cordella L, et al.Neuroprotective effect of reduced glutathione on oxaliplatin-based chemotherapy in advanced colorectal cancer. A randomized, double-blind, placebo-controlled trial[J]. J Clin Oncol,2002,20:3478-3483
