布地奈德、可必特加氨溴索雾化治疗毛细支气管炎疗效观察

To Observe the Efficacy of Aerosol Inhalation with Budesonide,Combivent and Ambroxol for Bronchiolitis

目的:探讨布地奈德、可必特(沙丁胺醇加异丙托溴铵)、氨溴索雾化吸入治疗毛细支气管炎的疗效。方法:112例毛细支气管炎患儿分为治疗组60例和对照组55例,在相同的综合治疗基础上,对照组仅常规使用激素,治疗组在对照组治疗基础上加用雾化吸入,雾化吸入药物为布地奈德悬液1mL、可必特1.25mL、氨溴索7.5mg加生理盐水2mL,以空气压缩泵雾化吸入,每日2次,连续用药3～5d。结果:治疗组治愈40例(66.7%),好转16例(26.7%),无效4例(6.6%),总有效率93.3%;对照组治愈30例(57.7%),好转15例(28.8%),无效7例(13.5%),总有效率86.5%。两组总有效率比较差异有统计学意义(P<0.05)。结论:布地奈德、可必特加盐酸氨溴索雾化吸入治疗毛细支管炎起效快,疗效确切,方法简单,患儿依从性好。

Objective：To investigate inhalation of aerosol ambroxol,budesonide,salbutamol plus ipratropium bromide in treatment of bronchiolitis. Methods：One hundred and twelve patients with bronchiolitis were divided into a treatment group and a control group. Only the routine use of hormone treatment was used in the control group after the same comprehensive treatment used for both,while the treatment group was nebulized additionally with 1 mL of budesonide suspension,1.25 mL of combivent （salbutamol＋ipratropium bromide）,7.5 mg of ambroxol and 2 mL of normal saline in the way of compressed aerosol inhalation,2 times a day for 3～5 d. Results：In the treatment group,40 cases （66.7%） were cured,16 cases （26.7%） improved and 4 cases （6.6%） void,with a total effective rate of 93.3%. In the control group,30 cases （57.7%） were cured,15 cases （28.8%） improved,7 cases （13.5%） void with a total effective rate of 86.5%. The difference in the total effective rates between the two groups was significant （P 0.05）. Conclusions：Budesonide,combivent and ambroxol hydrochloride inhalation treatment of capillary bronchitis is simple and effective for children.