草分枝杆菌局部注射治疗寻常疣的疗效观察

Efficacy of Local Injection of Mycobacterium Phlei F.U.36 in Treating Verruca Vulgaris

目的:观察草分枝杆菌局部注射治疗儿童寻常疣的疗效和安全性。方法:53例确诊为寻常疣患儿分为治疗组30例和对照组23例。治疗组在常规消毒下给予1.72μg/mL草分枝杆菌局部注射,直至疣体局部皮肤发白,每次注射间隔1～2周并观察其疗效;对照组采用激光烧灼疣体,6月～1年随访。结果:治疗组寻常疣治愈28例(93.3%),有效1例(3.3%),无效1例(3.3%),无1例复发,均未发现明显不良反应;对照组治愈20例(87.0%),复发3例(13.0%),萎缩性疤痕20例(87.0%),色素沉着2例(8.7%)。结论:草分枝杆菌局部注射治疗寻常疣安全、有效,复发率低。

Objective：To observe the efficacy and safety of local injection of mycobacterium phlei F.U.36 in treatment of child verruca vulgaris. Methods：Fifty-three patients with verruca vulgaris were divided into two groups. The treatment group （n=30） were treated with 1.72 μg/mL mycobacterium phlei F.U.36 after conventional disinfection,once every 1～2 weeks. The control group （n=23） were treated with carbon dioxide laser ablation. All patients were followed up for 6～12 months. Results：The curative rate of the treatment group was 93.3%,the effective and ineffective rate were both 3.3% ,and no one relapsed. The curative rate,recurrence rate,incidence rate of scar and pigmentation of the control group was 87.0%,13.0%,87.0% and 8.7%,respectively. Conclusions：Local injection of Mycobacterium Phlei F.U.36 for verruca vulgaris is effective and safe,with less recurrence than carbon dioxide laser ablation.