哮喘发病与“瘀”的关系探讨

Asthma morbidity and ＂stasis＂ relational research.

目的 本文探讨＂瘀＂与哮喘发病之间的关系,以明确＂瘀＂是否为哮喘发病的机理之一.方法 选择哮喘急性发作期患者84例为哮喘组,另选择非哮喘患者63例为对照组.检测入选者外周血中的血栓素A2（Thromboxane A2）、纤维蛋白酶原激活剂（TPA）、纤溶酶原活化剂抑制物（PAI）、凝血功能.结果 ①两组比较,OR为2.950,95%CI为（1.504,5.785）,哮喘组有瘀证表现的疾病危险性为无瘀证表现的2.95倍.②两组之间血液流变学各指标比较,TPA（P＞0.05）无统计学意义,TXA2、PAI凝血功能有统计学意义（P均＜0.05）,提示哮喘组的血流变学检测指标变化明显.结论 ①＂瘀＂与哮喘发病有关;②为以活血化瘀方药治疗哮喘提供了依据.

Methods Acute attack of asthma patients with 84 patients, divided into virtual Asthma Group, the other card-based group, another non-choice of 63 patients with asthma, as a control group. Detection of all selected in the peripheral blood TXA2; TPA, PAI; blood coagulation. Results ①asthma group and control group case-control study results： OR=2.950, 95% CI （1.504, 5.785） exposure risk of the disease as non-exposed group of 2.95 times. ②Asthma group and the control group between the various indicators of hemorheology, in addition to TPA （P〉0.05） no significant difference. Ms indicators are significant differences （P〈0.05）, suggested that asthma in the blood change detection indicators relative to the control group have changed significantly. Conclusion ①＂Stasis＂ and asthma-related, ＂Stasis＂ Asthma is a major cause of morbidity. ②From stasis treatment of asthma, Huoxue Huayu Prescription provide the basis for the treatment of asthma.