银杏达莫注射液与前列地尔注射液治疗急性脑梗塞的疗效比较

Effect of GLEDI and alteplase on acute ischemic stroke

目的 比较银杏达莫注射液和前列地尔注射液治疗急性脑梗塞的疗效.方法 将我院收治的120例患者随机分为银杏达莫组和前列地尔组,分别按疗程给予两种药治疗.观察神经功能缺损评分改变和血液流变学变化.结果 两组在治疗前后神经功能缺损评分均有统计学意义上（P＜0.05）,两组总有效率无统计学差异（P＜0.01）.银杏达莫组和前列地尔组的全血黏度高切变、全血低切变、血沉在治疗后均降低,有统计学意义（P均＜0.05）.银杏达莫组的血沉下降幅度更大（P＜0.05）.结论 银杏达莫和前列地尔均可有效治疗急性脑梗塞,按疗程使用疗效相当.

Objective To compare effect of GLEDI and alteplase on acute ischemic stroke. Methods 120 patients were randomly recruited into a GLEDI group and a alteplase group, and treated with the corresponding medicine respectively.The changes of NIHSS and hemorheology were observed. Results NISS and hemorheology in both groups were declined.There was statistic difference （P〈0.05）. The GLEDI group had a greater decline in ESR than the alteplase group, showing statistic difference （P〈0.05）. Conclusion Both GLEDI and alteplase were effective in treating acute ischemic stroke. They have relatively same effects ifthey were used to a full therapeutic course.