银杏达莫注射液对糖尿病肾病微量白蛋白尿的影响

Effect of Ginkgo Biloba Extract Injection on urinary albumin excretion in patients with diabetic nephropathy

目的 探讨银杏达莫注射液对糖尿病肾病尿蛋白排泄率的影响.方法 选择糖尿病肾病患者90例分为A、B两组.A组为微量白蛋白尿组,B组为大量白蛋白尿组.两组均静脉滴注银杏达莫注射液15 ml,1次/d,4周为1个疗程,同时维持原降糖约物治疗,比较两组治疗前后尿蛋白的变化.结果 A组尿蛋白排泄率显著降低（P＜0.01）.结论 银杏达莫注射液可降低尿微量白蛋白,对糖尿病肾病早期有一定治疗作用.

Objective To observe the effect of Ginkgo Biloba Extract Injection on urinary albumin excretion rate in patients with diabetic nephropathy （DN）. Methods A total of 90 patients with DN were divided into two groups： group A was micro-urinary-albumin group; group B was multiple-urinary-albumin group. Both groups were treated with routine therapy plus Ginkgo biloba extract injection （at a dose of 15ml） q.d. for 4 consecutive weeks. The urinary albumin excretion rate was compared between the two groups before and after treatment. Results As compared with the group B, urinary albumin excretion rate was significantly lowered in the group A （P〈0.01）. Conclusion Ginkgo Biloba Extract Injection had effects in lowering microalbumin in urine and therapeutic effect for patients with early DN.