妊娠高血压孕妇血脂代谢变化研究

Studies the changes of pregnancy-induced hypertension in lipid metabolism.

目的探讨妊娠高血压与血脂代谢变化的关系。方法对妊娠高血压孕妇轻度、中度、重度各30例进行血甘油三酯(TG)、载脂蛋白A(APO-A)、载脂蛋白B(APO-B)、低密度脂蛋白-胆固醇(LDL-C)、高密度脂蛋白-胆固醇(HDL-C)水平测定,同时选择30例无妊娠并发症的健康孕妇作为对照组。结果妊娠高血压组血TG高于对照组(P<0.01)。APO-A、HDL-C低于对照组(P<0.05)。APO-B明显高于对照组(P<0.01),LDL-C也高于对照组(P<0.05)。且上述变化随着病情的加重而进一步发展。结论高TG血症、APO-A、HDL-C水平降低、APO-B、LDL-C增高与妊娠高血压发病有关。

Objective：To study the relasionship between the changes in metabolism of Lipid and pregnency induced hypertension.Methods：The contens of Triglyceride aplipoprotein A aplipoprotein B High dencsty lipoprotein-cholesterol Low density lipoprotein-cholesterol in maternal and umbilical venw of pregnant induced hypertension and the normal pregnant women were measureed.Results：The level of the group of pregnency induced hypertension Triglyceride is higher than normal pregnency（P0.01）.the level of APO-B of the group of pregnency induced hypertension is significantly higher than normal pregnency（P0.01）,LDL-C is higher than normal pregnency（P0.05）.And were incresing with pregnency induced hypertension developing.Conclusion：High level of Triglyceride,high level of APO-B LDL-C and low level of APO-A HDL-C was associated with pregnency induced hypertension.