不同病因不孕症宫腔内人工授精1640周期疗效分析

Clinical analysis on intrauterine insemination due to different causes.

目的分析不同病因不孕症行夫精宫腔内人工授精(AIH/IUI)的疗效。方法对2007年1月-2007年12月在浙江省妇保院生殖中心门诊1244对不孕症实施治疗1640周期,根据不同的病因分析比较统计临床妊娠率。结果每周期的临床妊娠率为11.10%,每例临床妊娠率为14.63%。原发不孕组妊娠率高于继发不孕妊娠率(18.4%对9.7%),管性因素不孕组临床妊娠率(4.4%)显著低于不明原因(25.08%)、排卵障碍(18.48%)、男性因素(12.59%)和子宫内膜异位症组(12.62%)(P<0.01),后四组妊娠率差异无显著性但以不明原因组最高。女方年龄影响妊娠率。结论夫精宫腔内人工授精(AIH/IUI)治疗非输卵管因素引起不孕疗效甚佳。

Objective： To observe the clinical efficacy of intrauterine insemination（AIH / IUI） due to different causes of infertility.Methods： The clinical pregnancy rate of 1640 cycles in 1244 couples undergoing intrauterine insemination,in Zhejiang Province Women＇s Hospital Fertility Center Infertility implementation from January 2007 to December 2007,was statistical analyzed and compared.And all couples were divided according to different causes of infertility;the clinical pregnancy rate was compared.Results： The clinical pregnancy rate was 11.10% per cycle and 14.63% per patient.The clinical pregnancy rate of primary infertility group was higher than that of secondary infertility group（18.4% versus 9.7%）.The clinical pregnancy rate（4.4%） of tube factor infertility was significantly lower than that of unexplained（25.08%）,ovulation disorder（18.48%）,male factors（12.59%）,and endometriosis（12.62%）,within the different groups（P0.01）.The clinical pregnancy rate of the four latter groups wasn′t significantly difference,but that of unexplained was the highest.Women′s age affect the pregnancy rate.Conclusion： AIH / IUI has a very satisfying effect to treat the infertility causing by non-tubal factors.