摘要
目的:观察咪唑安定或/和曲马多在术后镇痛中的作用。方法:分别于硬膜外注入布比卡因(对照组,Ⅰ组,n=20),布比卡因和咪唑安定(Ⅱ组,n=25),布比卡因和曲马多(Ⅲ组,n=25)及布比卡因、咪唑安定和曲马多(Ⅳ组,n=25),比较术后镇痛效果。结果:布比卡因咪唑安定具有较好的术后镇痛效果。布比卡因加用咪唑安定和曲马多联用可提供更好的术后镇痛作用,并可明显减少阿片类药物用量。加用咪唑安定后主要副作用为嗜睡。结论:咪唑安定或/和曲马多与布比卡因硬膜外注射。
Objective: To evaluate the effect of midazolam and tramadol in postoperative analgesia. Methods: The postoperative analgesic effect was compared among epidural bupivacaine (group Ⅰ, n= 20), bupivacaine midazo1am (group Ⅱ, n= 25), bupivacaine tramadol (group Ⅲ, n= 25) and bupivacaine midazolam with tramadol (group Ⅳ, n= 25). Results: Epidural bupivacaine midazolam had better postoperative analgesic effect than bupivacaine alone. Epidural bupivacaine, midazolam with tramadol in combination provided a much effective postoperative analgesia, thus the narcotic requirements were signifi cantly reduced. The major side effect of epidural midazolam was somnolence. Conclusion: Midazolam and/or tramadol can be used in combination with bupivacaine epidurally, their postoperative analgesia effects are thus augmented.
出处
《临床麻醉学杂志》
CAS
CSCD
1999年第2期80-82,共3页
Journal of Clinical Anesthesiology