期刊文献+

乳腺癌阳性淋巴结比例与预后关系的研究 被引量:4

下载PDF
导出
摘要 目的:研究乳腺癌淋巴结阳性比例(positive-lymphnode rate,PLR)与预后的关系。方法:收集1989~1995年1221例淋巴结阳性的乳腺癌患者的临床、病理资料,分析PLR对总体生存率的影响,及根据淋巴结阳性数目分组的各亚组中PLR对生存率的影响。结果:PLR与生存率呈负相关,PLR越大预后越差。各分组PLR的界值不同,阳性淋巴结数1-3组、4-9组、10以上组,界值分别为0.2、0.4、0.6;组间差异均具有显著性(P均<0.05)。结论:PLR是预后危险因素,尽管PLR与阳性淋巴结数目呈正相关,但是在相同淋巴结阳性数目亚组内PLR对预后仍有不利影响,对不同阳性淋巴结数目患者,应采用不同界值对预后进行评价。
作者 高宇
出处 《实用医学杂志》 CAS 北大核心 2010年第19期3546-3548,共3页 The Journal of Practical Medicine
  • 相关文献

参考文献9

  • 1Krag D N, Single R M. Breast cancer survival according to number of nodes removed [J]. Ann Surg Oncol, 2003,10 (10) : 1152-1159.
  • 2Vinh-Hung V, Verschraegen C, Promish D I, et al. Ratios of involved nodes in early breast cancer [J]. Breast Cancer Res, 2004,6 (6) : R680-688.
  • 3Hatoum H A, Jamali F R, El-Saghir N S, et al. Ratio between positive lymph nodes and total excised axillary lymph nodes as an independent prognostic factor for overall survival in patients with nonmetastatic lymph node-positive breast cancer [J]. Annals of Surgical Oncology, 2009,16 (12) :3388- 3395.
  • 4Martinez-Ramos D, Escrig-Sos J, Alcalde-Sanchez M, et al.Disease-free survival and prognostic significance of metastatic lymph node ratio in T1-T2 N positive breast cancer patients. A population registry-based study in a European country [J]. World J Surg, 2009,33(8) : 1659-1664.
  • 5Lale Atahan I, Yildiz F, Ozyigit G, et al. Percent positive axillary lymph node metastasis predicts survival in patients with non-metastatic breast cancer [J]. Acta Oncol, 2008,47(2): 232-238.
  • 6Danko M E, Bennett K M, Zhai J, et al. Improved staging in node-positive breast cancer patients using lymph node ratio: results in 1,788 patients with long-term follow-up [J]. J Am Coll Surg, 2010,210(5) :797-807.
  • 7Yildirim E, Berberoglu U. Lymph node ratio is more valuable than level III involvement for prediction of outcome in node- positive breast carcinoma patients [J ]. World J Surg, 2007,31 (2) :276-289.
  • 8Vinh-Hung V, Verkooijen H M, Fioretta G, et al. Lymph node ratio as an alternative to pN staging in node-positive breast cancer [J]. J Clin Oncol, 2009,27(7):1062-1068.
  • 9Truong P T, Vinh-Hung V, Csemi G, et al. The number of positive nodes and the ratio of positive to excised nodes are significant predictors of survival in women with micrometastatic node-positive breast cancer [J]. Eur J Cancer, 2008,44(12): 1670-1677.

同被引文献34

  • 1朱亚东.乳腺癌术后无瘤生存率的影响因素及腋窝淋巴结检测数目的临床意义[J].实用癌症杂志,2014,29(2):222-225. 被引量:8
  • 2朱旭生,邹德环,梁培炎,李群.^(18)F-FDG符合线路显像在原发性胃癌诊断中的应用[J].中国肿瘤,2007,16(3):180-183. 被引量:2
  • 3卢毅,陈体江.乳腺癌改良根治术32例临床分析[J].中国基层医药,2007,14(3):501-501. 被引量:1
  • 4Scheidhauer K, Walter C, Seemann M D. FDG PET and other imaging modalities in the primary diagnosis of suspicious breast lesions [J]. Eur I Nucl Med Mol Imaging, 2004, 31( SuppI 1 ) : S70-S79.
  • 5Zangher I B, Messa C, Pie, ehio M, et al. PET/CT and hreast cancer[J]. Eur J NuclMedMd Imaging, 2004, 31 (Suppl 1): S136 - S142.
  • 6Bar-Shalom R, Valdivia A Y, Blauibx M D. PET imaging in oncology [J]. Semin Nucl Med, 2000,30(3):150-185.
  • 7Dent R,Trudeau M,Pritchard KI,et al. Triple-negative breast cancer: clinical features and patterns of recurrence[J]. Clin Cancer Res,2007,13 (15 Pt 1 ) :4429-4434.
  • 8Carey LA,Perou CM,Livasy CA,et al. Race,breast cancer subtypes,and survival in the Carolina Breast Cancer Study[J]. JAMA,2006,295 (21): 2492-2502.
  • 9Steponaviciene L, Lachej-Mikeroviene N, Smailyte G,et al. Triple negative breast cancer:adjuvant chemotherapy effect on survival[J]. Adv Med Sci, 2011,56 ( 2 ) : 285-290.
  • 10Hemandez-Aya LF, Chavez-Macgregor M,Lei X, et al. Nodal status and clinical outcomes in a large cohort of patients with triple-negative breast cancer[J]. J Clin Oncol, 2011,29 ( 19 ) : 2628-2634.

引证文献4

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部