1986-2008年沧州市肾综合征出血热疫情动态及监测结果分析

Epidemic dynamics and monitoring results of hemorrhagic fever with renal syndrome in Cangzhou city,1986-2008

目的分析1986-2008年沧州市肾综合征出血热(HFRS)疫情动态,评价预防控制措施效果。方法对资料进行描述,分析HFRS疫情动态、流行特征及相关监测结果。结果沧州市HFRS疫情呈现从低发、波动上升、下降的流行趋势。1986年首次报告该病,1999年和2002年出现2个高峰,发病率分别为14.78/10万和14.51/10万,其中89%的县(市)处在中发县标准以上,发病率在6.93/10万～42.02/10万之间,男女发病之比为2.07∶1,发病年龄向低龄和高龄两端延伸,病例主要分布在15～64岁之间,占91.37%。监测人群抗体平均阳性率为8.69%;平均鼠密度为2.20%;平均鼠带病毒率为8.61%。结论通过贯彻"灭鼠和免疫并重"策略,加强监测预警,结合健康教育等综合性防控措施,HFRS得到有效控制,2006年后发病率保持在1/10万以下。

Objective To analyze the epidemic dynamics of hemorrhagic fever with renal syndrome（HFRS）in Cangzhou city from 1986 to 2008,and to evaluate the effect of prevention and control measures.Methods Descriptive approaches were employed to analyze the epidemic dynamics,epidemiological characteristics and relevant monitoring results of HFRS.Results HFRS in the city was characterized by low incidence and frequent fluctuation.The first case was reported in 1986,followed by two incidence peaks in 1999 and 2002,with the incidence rates of 14.78/105 and 14.51/105.89% of counties（cities）had the incidence above the intermediate standard,ranging from 6.93 to 42.02 per 105.The sex ratio was 2.07∶1,with the age of onset extending to both ends of younger and older ages.Most patients were 15 to 64 years of age,accounting for 91.37%.The average antibody positive rate of the surveyed population was 8.69%.The average rat density was 2.20%,and averagely 8.61% of rats were carrying the virus.Conclusion Though the implementation of ＂Attaching Equal Importance to Rodent Control and Immunization Coverage＂ strategy in conjunction with strengthened monitoring and early warning,as well as publicized health education and other comprehensive measures,HFRS has been effectively controlled in the city with the incidence of less than 1/105 since 2006.