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糖皮质激素与实体瘤化疗耐药关系的研究现状

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摘要 糖皮质激素广泛用于肿瘤的一线治疗或辅助治疗,但有研究发现,糖皮质激素能诱导实体瘤对化疗耐药。本文就糖皮质激素与实体瘤化疗耐药关系的研究现状进行综述。
作者 丁凌雁 康马飞
机构地区 桂林医学院研究生学院 桂林医学院附属医院肿瘤内科
出处 《中国癌症防治杂志》 CAS 2010年第3期241-243,共3页 CHINESE JOURNAL OF ONCOLOGY PREVENTION AND TREATMENT
关键词 糖皮质激素 肿瘤 化学治疗 耐药性
分类号 R562.25 [医药卫生—呼吸系统]
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参考文献19

  • 1Machuca C,Mendoza-Milla C,Córdova E,et al.Dexamethasone protection from TNF-alpha-induced cell death in MCF-7 cells requires NF-kappaB and is independent from AKT[J].BMC Cell Biol,2006,7:9.
  • 2Mattern J,Büchler MW,Herr L Cell cycle arrest by glucocorticoids may protect normal tissue and solid tumors from cancer therapy[J].Cancer Bid Ther,2007,6(9):1345-1354.
  • 3Vogt A,McDonald PR,Tamewitz A,et al.A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptoeis in dexamethasone-protected cancer cells[J].Mol Cancer Ther,2008,7(2):330-340.
  • 4Sumikawa T,Shigeoka Y,Igishi T,et al.Dexamethasone interferes with trastuzumab-induced cell growth inhibition through restoration of AKT activity in BT-474 breast cancer cells[J].Int J Oncol,2008,32(3):683-688.
  • 5Wagenblast J,Baghi M,Mürtel S,et al.Does dexamethasone inhibit anticancer activity of cetuximab in squamous cell carcinoma cell lines of the head and neck[J]? Oncol Rep,2009,22(1):171-176.
  • 6Honorat M,Mesnier A,Di Pietro A,et al.Dexamethssone down-regulates ABCG2 expression levels in breast cancer cells[J].Biochem Biophya Res Commun,2008,375(3):308-314.
  • 7Redondo M,Téllez T,Roldan MJ,et al.Anticluserin treatment of breast cancer cells increases the sensitivities of chemotherapy and tamoxifen and counteracts the inhibitory action of dexamethasone on chemotherapy-induced cytotoxicity[J].Breast Cancer Res,2007,9(6):R86.
  • 8Wu W,Chaudhuri S,Brickley DR,et el.Microarray analysis reveals glucocorticoid-regulated survival genes that are associated with inhibition of apoptosis in breast epithelial cells[J].Cancer Res,2004,64(5):1757-1764.
  • 9Zhang C,Beckermann B,Kallifatidis G,et al.Corticosteroids induce chemotherapy resistance in the majority of tumour cells from bone,brain,breast,cervix,melanoma and neuroblastoma[J].Int J Oncol,2006,29(5):1295-1301.
  • 10Lien HC,Lu YS,Shun CT,et al.Differential expression of glucocoticoid receptor in carcinomas of the human digestive system[J].Histopathology,2008,52(3):314-324.

二级参考文献9

  • 1The Italian Group of Anticancer Research. Dexamethasone alone or in combination with ondansetron for the prevention of delayed nausea and vomiting induced by chemotherapy[J] . N Engl J Med,2000,342(21) : 1 554.
  • 2Herr I, Ucur E, Herzer K, et al. Glucocorticoid cotreatment induces apoptosis resistance toward cancer therapy in carcinomas[J]. Cancer Res ,2003,63(12) :3 112.
  • 3Zhang C, Marme A, Wenger T, et al. Glucocorticoid-mediated inhibition of chemotherapy in ovarian carcinomas [ J ]. Int J Oncol,2006,28(2) :551 .
  • 4Zhang C, Beckermann B, Kallifatidis G, et al. Corticosteroids induce chemotherapy resistance in the majority of tumour cells from bone, brain, breast, cervix, melanoma and neuroblastoma [J]. Int J Oncol,2006,29 (5) : 1 295.
  • 5Wang H, Wang Y, Rayburn ER, et al. Dexamethasone as a chemosensitizer for breast cancer chemotherapy: potentiation of the antltumor activity of adriamycin, modulation of cytokine expression, and pharmacokinetics [ J ]. Int J Oncol, 2007,30 (4) :947.
  • 6Schmidt S, Rainer J, Ploner C, et al. Glucocorticoid-induced apoptosis and glucocorticoid resistance:molecular mechanisms and clinical relevance [ J ]. Cell Death Differ, 2004, ( 11 Suppl) :S45.
  • 7Herr I, Gassler N, Friess H, et al. Regulation of differential pro- and anti-apoptotic signaling by glucocorticoids [ J ]. Apoptosis ,2007,12(2) :271.
  • 8Wu W, Chaudhuri S, Brickley DR. Microarray analysis reveals glucocorticoid-regulated survival genes that are associated with inhibition of apoptosis in breast epithelial cells [ J ]. Cancer Res ,2004,64(5) : 1 757.
  • 9Liu LZ, Zhou XD, Qian G, et al. AKT1 amplification regulates cisplatin resistance in human lung cancer cells through the mammalian target of rapamycin/p70S6K1 pathway[J]. Cancer Res ,2007,67(13) :6 325.

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中国癌症防治杂志
2010年 第3期

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