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前列腺增生与Bcl-2基因表达的相关性 被引量：1

Prostatic hyperplasia and Bcl-2 correlation of gene expression
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摘要 B细胞淋巴瘤/白血病-2(Bcl-2)基因是Bcl-2基因家族的一个重要成员。Bcl-2家族是细胞凋亡相关基因研究最多的一类蛋白质。Bc1-2基因不能改变细胞的增殖能力,而是通过抑制多种形式细胞的凋亡,延长细胞寿命而促进肿瘤的发生。近年来人们对调控凋亡基因的认识越来越深入。前列腺增生的发生和发展与前列腺细胞凋亡及其基因控制有关。本文就近年来Bcl-2基因的抗凋亡机制及其与BPH的关系两方面的研究进展进行综述,进一步探讨抗凋亡基因Bcl-2在BPH的发生、发展过程中所起的作用。 B cell lymphoma/leukemia Bcl-2（Bcl-2） gene is an important member of the gene families.Bcl-2 family is apoptosis related gene research most proteins.Bc1-2 gene cannot change the cell proliferation capacity,but by various forms cell apoptosis,prolong life and promote cell tumors.In recent years,people in the know more indepth apoptosis of genes.The occurrence and development of prostate hyperplasia of prostate and apoptosis and genetic control.In recent years,Bcl-2 gene antiapoptotic mechanisms and its relationship with the two aspects of BPH are reviewed,and further discusses antiapoptotic genes in Bcl-2 the occurrence and development of BPH.
作者 孙飞 曹余光
机构地区 辽宁医学院附属第三医院泌尿外科
出处 《中国医学工程》 2010年第3期169-171,共3页 China Medical Engineering
关键词 BCL-2基因 前列腺增生 细胞凋亡 Bcl-2 gene prostatic hyperplasia cell apoptosis
分类号 R697.32 [医药卫生—泌尿科学]
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参考文献20

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二级参考文献14

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中国医学工程
2010年 第3期

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