二氧化硫等离子体处理聚乙烯膜表面及抗凝血性能

Surface and Antithrombogenecity of Polyethylene Treated by Sulfur Anhydride Plasma

目的研究等离子体改性低密度聚乙烯（ＬＤＰＥ）膜表面的抗凝血性能．方法用二氧化硫（ＳＯ２）气体等离子体处理ＬＤＰＥ膜表面，通过接触角测试，研究磺酸基与表面浸润性、表面自由能之间的关系；用ＸＰＳ能谱、ＡＴＲ－ＦＴＩＲ对表面组成及结构进行表征，体外凝血试验分析表面抗凝血性能．结果ＳＯ２气体等离子体处理ＬＤＰＥ膜表面，可使磺酸基与ＬＤＰＥ表面分子共价结合，获得了具有抗凝血性能的表面分子结构．结论ＳＯ２气体等离子体处理ＬＤＰＥ的膜表面具有较好的抗凝血性．

Aim To investigate antithrombogenecity of low density polyethylene(LDPE) thin films treated by sulfur anhydride plasma. Methods LDPE thin films were treated by sulfur anhydride plasma. The relation of sulfonic group with surface soakage or hydrophilicity and surface free energy were studied by contact angle measurements. Surface composition was characterized with XPS and ATR FTIR spectroscopy. Antithrombogenecity of the surface was analyzed with blood coagulation measurements in vitro. Results Sulfonic group can covalently bind with the LDPE surface molecule by using the technique of sulfur anhydride plasma treatment and the molecular composition of the surface with antithrombogenecity was obtained. Conclusion LDPE thin films surface treated by sulfur anhydride plasma have a good antithrombogenecity.