摘要
目的:观察消瘤冲剂对lewis肺癌小鼠免疫功能的影响。方法:取C57BL/6J小鼠分别皮下接种lewis肺癌细胞悬液,给予消瘤冲剂按7.5g/kg、15.0g/kg、30.0g/kg三个剂量连续灌胃10天,分别观察抑瘤率、T淋巴细胞转化功能及巨噬细胞吞噬功能的影响。结果:消瘤冲剂能明显提高lewis肺癌小鼠T淋巴细胞转化功能(P<0.05,P<0.01)和巨噬细胞吞噬功能(P<0.05)。结论:消瘤冲剂具有提高lewis肺癌小鼠免疫功能的作用。
Objective:To observe the effect of Xiaoliu electuary on the immune function of Lewis lung cancer mice.Methods:Lewis lung cancer cells were subcutaneously injected in C57BL/6J mice.After lung cancer was induced,Xiaoliu electuary was intragastrically administered at doses of 7.5 g/kg,15.0 g/kg,30.0 g/kg for 10 days.Inhibition rate was calculated;T lymphocyte transformation test was performed and phagocytosis of macrophage was detected.Results:3H-TdR method showed that the T cell transformation had been improved in Lewis mice treated with 15.0 g/kg and 30.0g/kg Xiaoliu electuary as compared with Lewis model mice(P〈0.05,P〈0.01)and the changes of phagoytosis of macrophage was observed in the same pattern(P〈0.05).Conclusion:Xiaoliu electuary may be effective to improve the immune response in Lewis lung cancer mice.
出处
《浙江中西医结合杂志》
2010年第10期595-596,共2页
Zhejiang Journal of Integrated Traditional Chinese and Western Medicine
关键词
小鼠
LEWIS肺癌
抑瘤率
免疫功能
消瘤冲剂
mice Lewis lung cancer inhibition rate immune function Xiaoliu electuary