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普伐他汀联合罗格列酮上调冠心病患者单核细胞ABCA1表达

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作者 李华波
出处 《基础医学与临床》 CSCD 北大核心 2010年第10期1096-1097,共2页 Basic and Clinical Medicine
基金 湖北省教育厅科学技术研究计划中青年人才项目(B200792004)
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  • 1Oram JF.HDL apolipoproteins and ABCA1 partners in the removal of excess cellular cholesterol[J].Arterrioscler Thromb Vasc Biol,2003,23 (5):720-727
  • 2Chinett G,Lestavel S,Bocher V,Remaley AT,Neve B,Torra IP,et al.PPAR-α and PPAR-γ activators induce cholesterol from human macrophage foam cells through stimulation of the ABCA1 pathway[J].Nat Med,2001,7 (1):53-58
  • 3Chinetti G,Lestavel S,Fruchart JC,Clavey V,Staels B Peroxisome proliferator-activated receptor α (PPARα) reduces cholesterol esterification in macrophages[J].Circulation Research,2003,92 (2):212-217
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  • 5Brooks Wilson A,Marcil M,Clee SM,Zhang LH,Roomp K,van Dam M,et al.Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency[J].Nat Genet,1999,22 (4):336-345
  • 6Bodzioch M,Orso E,Klucken J,Langmann T,Bottcher A,Diederich W,et al.The gene encoding ATP-binding cassette transporter l is mutated in Tangier disease[J].Nat Genet,1999,22 (4):347-351
  • 7Smith JD,Le Goff WL,Settle M,Brubaker G,Waelde C,Horwitz A,et al.ABCA1 mediates concurrent cholesterol and phospholipid efflux to apolipoprotein A-I[J].J Lipid Res,2004,45 (4):635-644
  • 8Wang M,Wise SC,Leff T,Su TZ.Troglitazone,an antidiabetic agent,inhabits cholesterol biosynthesis through a mechanism independent of peroxisome proliferators-activated receptor-gamma[J].Diabetes,1999,48 (2):254-260
  • 9Hodgkinson CP,Ye S.Microarray analysis of peroxisome proliferator-activated receptor-gamma induced changes in gene expression in macrophages[J].Biochem Biophys Res Commun,2003,308 (3):505-510
  • 10Akiyama TE,Sakai S,Lambert G,Nicol CJ,Matsusue K,Pimprale S,et al.Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1,ABCG1,and apoE in macrophages and reduced cholesterol efflux[J].Mol Cell Biol,2002,22 (8):2 607-619

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