期刊文献+

展青霉素研究现状及其对中药安全性的影响 被引量:6

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摘要 展青霉素是一种由多种真菌产生的有毒代谢物,综述了展青霉素的来源、毒性及其相关的分析方法,并基于展青霉素的毒性研究,探讨展青霉素产生菌对中药材及其制剂侵染的危害,以期为建立中药安全性的评价体系提供依据,制定和形成药材生产、流通过程中防治微生物侵染的共性技术体系。
出处 《南京中医药大学学报》 CAS CSCD 北大核心 2010年第5期398-400,共3页 Journal of Nanjing University of Traditional Chinese Medicine
基金 国家科技重大专项重大新药创制(2009ZX09502-025)
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参考文献17

  • 1Saxena N,Ansari KM,Kumar R,et al.Patulin causes DNA damage leading to cell cycle arrest and apoptosis through modulation of Bax,p53 and p21/WAF1 proteins in skin of mice[J].Toxicology and Applied Pharmacology,2009,234(2):192-201.
  • 2贺玉梅,贾珍珍,董葵,杜娟,齐祖桐.展青霉素产生菌产毒性能研究[J].中国卫生检验杂志,2001,11(3):302-303. 被引量:18
  • 3Dombrink-Kurtzman MA,Blackburn JA.Evaluation of several culture media for production of patulin by Penicillium species[J].International Journal of Food Microbiology,2005,98(3):241-248.
  • 4Morales H,Sanchis V,Coromines J,et al.Inoculum size and intraspecific interactions affects Penicillium expansum growth and patulin accumulation in apples[J].Food Microbiology,2008,25(2):378-385.
  • 5Morales H,Marin S,Centelles X,et al.Cold and ambient deck storage prior to processing as a critical control point for patulin accumulation[J].International Journal of Food Microbiology,2007,116(2):260-265.
  • 6周克权,王君,刘秀梅.苹果汁中展青霉素和羟甲基糠醛的高效液相色谱测定方法[J].中国食品学报,2003,3(3):24-29. 被引量:17
  • 7Liu BH,Wu TS,Yu FY,et al.Mycotoxin patulin activates the p38 kinase and JNK signaling patulinhways in human embryonic kidney cells[J].Toxicological Sciences,2006,89(2):423-430.
  • 8Iwahashi H,Kitagawa E,Suzuki Y,et al.Evaluation of toxicity of the mycotoxin citrinin using yeast ORF DNA microarray and Oligo DNA microarray[J].BMC Genomics,2007,8:95.
  • 9Wu TS,Liao YC,Yu FY,et al.Mechanism of patulin-induced apoptosis in human leukemia cells (HL-60)[J].Toxicology Letters,2008,183(1-3):105-111.
  • 10Escoula L,Thomsen M,Bourdiol D,et al.Patulin immunotoxicology:effect on phagocyte activation and the cellular and humoral immune system of mice and rabbits[J].International Journal of Immunopharmacology,1988,10(8):983-989.

二级参考文献13

  • 1刘绘园,于孔玖.山楂及其制品中展青霉素的含量及污染的调查分析[J].中国食品卫生杂志,1995,7(4):42-42. 被引量:5
  • 2宋家玉,邢金川,林艺,吴南,王玉华.山东省部分水果及制品中展青霉素污染调查分析[J].中国食品卫生杂志,1995,7(2):43-44. 被引量:11
  • 3刘勇 胡文娟.苹果及其制品中展青霉素的薄层扫描测定法[J].卫生研究,1988,17(4):42-42.
  • 4刘勇 胡文娟.苹果及其制品中展青霉素的薄层扫描法[J].卫生研究,1988,17(4):42-46.
  • 5.GBl4974—1994.苹果及山楂制品中展青霉素的限量标准:中华人民共和国国家标准[S].,..
  • 6Llovera Montserrat, Viladrich Remei, Torres Merce, et al. Analysis of underivatizated patulin by a GC- MS technique[J]. Journal of Food Protection, 1999, 62 (2): 202-205.
  • 7Vero Silvana, Vazquez Alvaro, Pia Cerdeiras Maria, et al. A rapid TLC- scanning method for the determination of patulin in apple products [J]. Journal of Planar Chromato graphy, 1999, 12:172-175.
  • 8Bartolome B, Bengoechea ML, Perez -Ilzarbe [J], et al. Determination of patulin in apple juice by high - performance liquid chromatography with diode-array detection [J]. Journal of Chrorrmtography A, 1994, 644:39-43.
  • 9JT Edward, MS Peter. Determination of patulin by capillary gas chromatography of the heptafluorobutyrate derivative [J ].Journal of Chromatography, 1991, 538:441-446.
  • 10Liu Xiumei. Mycotoxins contamination of food in China [J]. Mycotoxins, 1996 (43): 1-7.

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