48例中药注射剂不良反应报告分析

Analysis of 48 adverse drug reactions induced by traditional chinese medicine injections

目的探讨中药注射剂不良反应发生的特点,为临床合理用药提供参考。方法对我院2007～2009年上报的48例中药注射剂不良反应进行回顾性分析。结果 48例中药注射剂不良反应报告中,>60岁者发生不良反应比例最高(占31.25%);临床表现以皮肤及其附件损害最常见(占45.83%);涉及12个中药注射剂品种。结论临床应慎重使用中药注射剂,加强对中药注射剂的监测,提高临床用药安全。

Objective Analyzed serious adverse drug reactions（ADR）of traditional Chinese medicine injections to provide the references information for rational drug in clinical practice.Methods 48 adverse drug reactions induced by traditional Chinese medicine injections reported from 2007to 2009 in the hospital have been analyzed retrospectively.Results Of the 45 ADR cases,31.25% occurred in patients aged above 60,and 45.83% manifested as lesions of skin and appendants.48 caese involve 12 infections.Conclusions ADR caused by traditional Chinese medicine injections should be con-cerned,and ADR should be intensively montored and treated timely.