5%高渗氯化钠液加羟乙基淀粉40注射液用于剖宫产腰麻后低血压疗效观察

Efficacy observation of 5% hypertonic saline solution plus hydroxyethyl starch 40 Injection in hypotension after spinal anesthesia for cesarean section

目的:观察5%高渗氯化钠液加羟乙基淀粉40注射液对剖宫产腰麻后低血压的疗效。方法:选择我院200例ASAⅠ～Ⅱ级择期行剖宫产手术患者,均采用5%高渗氯化钠液加羟乙基淀粉40注射液预防剖宫产腰麻后低血压。结果:本组200例在腰麻后5minSBP均有下降,尤以腰麻后20min较明显,腰麻后SBP变化与输注前比较,差异无统计学意义;输注后产妇PT、APTT、FIB及K+、Na+、Cl-浓度变化与输注前比较,差异无统计学意义;新生儿脐动脉血pH和电解质均在正常范围。结论:5%高渗氯化钠液加羟乙基淀粉40注射液是用于剖宫产腰麻后低血压的一种有效方法。

Objective： To observe the efficacy of 5% hypertonic saline solution plus hydroxyethyl starch 40 Injection in hypotension after spinal anesthesia for cesarean section. Methods： In our hospital, 200 cases （ASA Ⅰ-Ⅱ） undergoing cesarean section were selected, they applied 5% hypertonic saline solution plus hydroxyethyl starch 40 Injection to prevent hypotension after spinal anesthesia. Results： 200 cases in 5 min SBP after spinal anesthesia had declined, especially after spinal anesthesia 20 min obvious, the SBP changes after spinal anesthesia compared with before transfusion, there was no significant differences; after transfusion, the concentration change of PT, APTT, FIB and K＋, Na＋, Cl-compared with before transfusion, there was no significant differences; Umbilical artery blood pH and electrolytes were all in normal range. Conclusion： 5% hypertonic saline solution plus hydroxyethyl starch 40 Injection in hypotension after spinal anesthesia for cesarean section is an effective method.