摘要
内皮祖细胞在缺血组织的血管形成及损伤血管的内皮再生中起重要作用。细胞因子作为血管形成中微环境的重要组成，对内皮祖细胞的调控发挥重要作用，有效应用对内皮祖细胞发挥正性调控作用的细胞因子可明显提高内皮祖细胞的数量、生物学功能及其治疗效果。现就血管内皮生长因子等7种细胞因子对内皮祖细胞的调控机制进行综述。
Endothelial progenitor cells play a significant role in neovascularization of ischemie tissues and in reendothelialization of damaged blood vessels. Cytokines, an important components of micro- environment of angiogenesis, play an important role in regulation of endothelial progenitor cells. The effective application of cytokines can significantly argument the number, enhance the biological function and improve the therapeutic effect of endothelial progenitor cells, which play a positive role in regulation of endothelial progenitor cells. This article briefly reviewed the regulating mechanisms of the vascular endothelial growth factor and other cy- tokines in a total of 7 endothelial progenitor cells.
出处
《国际外科学杂志》
2010年第10期684-687,共4页
International Journal of Surgery
基金
基金项目：福建省自然科学基金资助（No.2009J01186）
关键词
血管形成
细胞因子
内皮祖细胞
Angiogenesis
Cytokines
Endothelial progenitor cells
