白藜芦醇的合成研究进展

Advances in the research of resveratrol synthesis

白藜芦醇是一种具有抗病及多种保健功能、有益于人类健康的非黄酮类多酚化合物,从天然植物中获取大量白藜芦醇面临着资源短缺的问题。人工合成白藜芦醇主要有两类方法:化学合成和生物合成。化学合成主要有:Perkin反应合成白藜芦醇,Witting和Witting-Homer反应合成白藜芦醇,Heck反应合成白藜芦醇,利用碳负离子与羰基化合物的缩合反应合成白藜芦醇等方法。生物合成主要有:植物细胞悬浮培养技术生产白藜芦醇,芪合酶转基因技术。

Resveratrol is a kind of non-flavonoids polyphenolic compound which with had functions of disease resistance and health care for human.The plants resources containing resveratrol are scarce and lacking plants.There are two artificial synthesis for resveratrol： chemical synthesis and biosynthesis.The chemical synthesis methods are Perkin action,Witting and Witting-Homer action,Heck action and,carbanion and carbonyl compound condensation.The biosynthesis methods are plant cell suspension culture and stilbene synthase transgenic technology.