摘要
目的：了解反复发作抑郁症患者的甲状腺激素水平。方法：按性别、年龄１：１匹配选取序贯就诊的患者和健康者各２８例，采用放射免疫法测定患者组治疗前、后和对照组血清Ｔ３、Ｔ４、ｒＴ３和ＴＳＨ浓度。结果：患者组治疗前、后血Ｔ４水平（１３５．４±２２．０ｎｇ／ｍｌ和１１３．１±２０．３ｎｇ／ｍｌ）明显高于对照组（１０３．９±１０．３ｎｇ／ｍｌ），治疗后Ｔ４明显下降；治疗前Ｔ４与ＨＡＭＤ评分呈显著性正相关（ｒ＝０．４１，Ｐ＜０．０５）。结论：反复发作抑郁症Ｔ４升高继发于情绪障碍。
Objective: To examine the relationship
between serum thyroid hormone levels and recurrent depression. Method: Blood for serum T3,
T4, rT3 and TSH were taken in 28 patients with recurrent depression before and after treatment
with PEG. Patients were monitored with HAMD scales. 28 normal subjects matched in age and
sex were recruited as controls. Results: Serum level in patient group decreased significantly
with treatment (pretreatment=1354220ng/ml,posttreatment=1131203ng/ml). Both were higher
than normal controls (1039103ng/ml). There was positive correlation between pretreatment T4
level and HAMD scores (r=041, P<005). Conclusion: Raised T4 level may be induced by
recurrent depressive episodes. Pretreatment T4 level could be useful predictor for severity of
depression.
出处
《临床精神医学杂志》
1999年第3期147-148,共2页
Journal of Clinical Psychiatry
关键词
反复发作
抑郁症
甲状腺激素
Recurrent depressive episodesThyroid hormones
