2006-2009年医院头孢菌素类药物利用分析

Utilization of Cephalosporins in Hospital During 2006-2009

目的了解医院头孢菌素类药物的临床使用情况及用药趋势,为临床合理用药提供科学依据。方法对成都6家三甲综合医院2006—2009年头孢菌素类药物的用量、销售金额、用药频度(DDDs)等进行统计分析。结果第一代头孢、第二代头孢与氧头孢类用量逐年增加,第三代头孢菌素用药金额最高,仍占临床用药的绝对主导地位,头孢美唑、头孢米诺及头孢硫脒的消费金额逐年递增。DDDs排序头孢克洛、头孢克肟、头孢呋辛连续4年位居前列。结论医院应用头孢菌素总体基本合理,应控制三代头孢及其复方制剂、氧头孢的用量。

Objective To learn the situation and tendency of cephalosporins usage in hospitals,in order to offer the scientific basis for clinical medication reasonably.Methods The data of dosage,sales amount and daily defined doses（DDDs） of cephalosporins in 6 hospitals at 3A grade in Chengdu city during 2006-2009 were statistically analyzed.Results The usages of the first and second generation cephalosporins as well as Oxacephems were increased year by year,and the sales amount of the third generation cephalosporins was highest,occupying the absolutely dominant place in clinical administration.The consumption qualities of Cefmetazole and Cefiminox were increased obviously year by year.The DDDs of Cefaclor,Cefixime and Cefuroxime occupied the first three places for four consecutive years.Conclusion The situation of the usage of cephalosporins in hospital is generally reasonable.The dosages of the third generation cephalosporins,their compound preparations and Oxacephems must be controlled.