小儿先天性心脏病术后感染相关因素分析

Analysis of Infection-related Factors after Pediatric Cardiac Operations

目的:分析小儿先天性心脏病术后感染的相关因素,为临床用药、护理及治疗提供依据。方法:对2008年9月～2009年5月期间,进行先天性心脏病手术、满足入选条件的患儿346人,进行回顾性分析,根据发生感染与否将患儿分为感染组(39人)和对照组(307人);将可能的危险因素先进行单因素分析,在此基础上进行多因素Logisitic回归分析。结果:两组患儿在年龄、术前住院时间、体重等17个指标上的差异有统计学意义(P<0.05);多因素Logisitic回归分析表明肺动脉高压、恢复室停留≥120 h、体外循环时间≥120 min、机械通气时间≥120 h、频繁的吸痰是发生感染的独立危险因素。结论:多种因素导致先心病患儿术后发生感染,必须采取综合性的预防措施才能有效控制。

Objective： To analyze infection - related factors after pediatric cardiac operations. Method：346 cases with pediatric cardiac operations from September 2008 to May 2009 were divided into an infection group （39 cases） and a controlled group（307 cases）. Pre-, intra-, and postoperative factors were collected and analyzed between the two groups, and the multivariate analysis（ logistic regression） was used to identify the risk factors of infection. Result：The two groups showed marked statistical differences （P 〈 0.05 ） in age, hospitalization time before operation, body weight, etc. The mul- tivariate 1 ogistic regression analysis indicated that pulmonary hypertension, lenglh of recovery room ≥ 120 h, duration of extracorporeal circulation ≥ 120 m , duration of mechanical ventilation ≥120 h , and suction sputum frequency were the independent risk factors for the infection. Conclusion：The infection was induced by multiple factors. A comprehensive meas- ure should be taken to control its occurrence.