2007～2009年我院质子泵抑制剂利用调查

Utilization of Proton Pump Inhibitors in our Hospital During the Period of 2007-2009

目的:了解我院近年来质子泵抑制剂(PPIs)的应用情况及趋势。方法:对PPIs的品种、销售金额、用药频度(DDDs)、日均费用(DDC)进行综合分析。结果:2007～2009年我院PPIs的销售金额占消化系统销售金额的40%以上,每年以20%～30%的速度增长,高于整个消化系统用药的增长速度;口服PPIs DDDs比例为85%,DDC 7.28～7.91元,注射PPI s DDDs比例为15%,DDC 61.14～71.70元;销售金额前3位是:奥美拉唑钠(Ⅳ)两个国产品种和雷贝拉唑;DDDs前3位:奥美拉唑(奥克)、雷贝拉唑和兰索拉唑。结论:PPIs是一类发展潜力巨大的药物,兰索拉唑增长速度最快,我院PPIs的使用基本合理。

Objective： To evatuate the utilization and tendency of proton pump inhibitors （PPIs） used in our hos- pital during 2007 - 2009. Method： The use of PPIs was retrospectively analyzed in our hospital during 2007- 2009 in terms of drug varieties, consumption sum, medication frequency （ DDDs）, average daily cost （ DDC ）, etc. Result： The percentage of the consumption sum of PPIs in all digestive system drugs kept over 40%. The annual increase of the consumption sum of PPIs was 20% -30% from 2007 to 2009 ,which was over that of all digestive system drugs. The percent- age of oral PPIs was 85% in term of DDDs and its DDC was 7.28 -7.91 yuan. The percentage of PPIs for injections was 15% in term of DDDs and its DDC was 61.14 -71.70 yuan. The top three of consumption sum in single PPI were two do- mestic varieties of omeprazole for injection and rebeprazolc. The top three of DDDs in single PPI were omeprazole （ domestic, po）, rebeprazole and lansoprazole. Conclusion：PPIs had great potentiality for development, and the annual increase speed of lansoprazole was the fastest. The clinical application of PPIs in our hospital was reasonable.