不同区域女性阴道念珠菌感染分析284例

The Analysis of 284 Female Cases with Vaginal Candida Infection in the Different Regions

目的了解阴道念珠菌病患者不同区域女性阴道念珠菌感染及耐药现状。方法通过广汉市第二人民医院妇产科对阴道念珠菌患者采取阴道分泌物余片,经革兰染色镜检菌株,然后进行鉴定及药敏试验。结果本文共鉴定284株念珠菌,其中白色念珠菌检出率占首位87.1%,其次光滑念珠菌检出率11.4%。药敏结果显示,白色念珠菌对5-氟胞嘧啶、衣曲康唑、氟利康唑、制霉素耐药率均<30.5%,较敏感,氟康唑率均>51.3%以上,总耐药率>56.8%以上,敏感性较差。而光滑念珠菌对5-氟胞嘧啶、氟康唑、氟利康唑、衣曲康唑、制霉菌素耐药率均<23.1%,敏感性较好,光滑念珠菌对氟康唑耐药率100%,不敏感。结论白色念珠菌和光滑念珠菌是主要的阴道致病菌,不同种类耐药性有所差异,城市与农村女性的感染率,复发率有差异,应加强病原菌的耐药性检测。

Objective To understand the status of patients with vaginal infection and drug resistance.Methods The clinical symptoms of Obstetrics and Gynecology hospital patients to take than tablets vaginal secretion by Gram staining,Gram-positive spore can be seen and pseudohyphae and hyphae.For Candida culture,identification and sensitivity test.Results A total of 284 Candida identified,of which Candida albicans accounted for 87.1%,Candida glabrata 11.4%.Susceptibility results showed that Candida albicans to 5-fluorocytosine,clothing,itraconazole,fluorine Likangyl,nystatin resistance rate 30.5%,more sensitive to fluconazole rate 51.3% and the total resistance drug ratio 56.8% more than lower sensitivity.The Candida glabrata to 5-fluorocytosine,fluconazole,fluorine Likangyl,clothing itraconazole,nystatin resistance rate 23.1%,sensitivity is better,Candida glabrata resistance to fluconazole 100%,not sensitive.Conclusion Candida albicans and Candida glabrata vaginal pathogens are the main different types of resistance have different infection rates between urban and rural women,the recurrence rate are different,common bacteria as commonly used in clinical drug resistance increased continuously,a serious bacterial resistance,the resistance should be enhanced detection of pathogens.