摘要
目的:观察清开灵注射液治疗小儿急性热证的疗效。方法:将126例急性热证患儿随机分为治疗组96例和对照组30例。治疗组采用清开灵注射液静滴;对照组用病毒唑静滴,每日1次。2组常规治疗基本相同。结果:治疗组治愈83例(86.5%)、显效10例(10.4%)、有效3例(3.1%),总有效率100.0%;对照组治愈13例(43.3%)、显效8例(26.7%)、有效5例(16.7%)、无效4例(13.3%),总有效率86.7%。2组治愈率和总有效率均有显著性差异(P均<0.01)。结论:清开灵注射液治疗小儿急性热证具有疗效好、治愈率高、无明显毒性及不良反应等特点,故可作为治疗小儿急性热证的首选药物之一。
Objective :To observe the curative effects of Qingkailing Injection (QKLI) on acute febrile symptoms of children. Methods :126 cases with acute febrile symptoms were randomly divided into treatment group (n=96) and control group (n=30).The treatment group was treated with QKLI infused intravenously once a day but the control group treated with virazole infused intravenously once a day.The conventional therapy was basically same for both two groups. Results :In treatment group 83 cases were cured (865%),10 cases markedly effective (104%),and 3 cases effective (31%),but 13 cases (433%),8 cases (267%),and 5 cases (167%) respectively and 4 cases were ineffective (133%).In comparison between two groups the differences in cured and total effective rates(1000% vs.867%) were significant (all P<001). Conclusions :QKLI in treating acute febrile symptoms of children possesses the following characters,high cured rate,having not obvious toxic and side effects.It can be used as one of the first selected drugs.